Developing ASIC1-targeted therapeutic candidates for ischemic injury

A preclinical biotechnology company advancing differentiated peptide and formulation-based approaches for acute neurological and cardiovascular indications

Yatrex Pharmaceuticals is a preclinical biotechnology company focused on developing novel therapeutic candidates targeting acid-sensing ion channel 1 (ASIC1), a key mediator of tissue injury under ischemic and acidic conditions.

The company’s pipeline combines proprietary tricyclic poly-arginine peptides with formulation-driven repurposing strategies, designed to support translational progress toward IND-enabling development.

Targeted Biology

Focused on ASIC1-mediated injury mechanisms with strong biological and translational rationale in ischemic disease.

Differentiated Modalities

A multi-asset pipeline spanning novel polycyclic peptide architectures and injectable formulation strategies.

Translational Discipline

Preclinical programs structured around pharmacokinetics, functional efficacy, and regulatory-aligned development milestones.